Polyneuropathy Of Unknown Etiology In An Adult Female With Anatomic Variants

One of the earliest descriptions neuralgia dates back to John Fothergill in 1773.1 However, concept nerve pain can be traced physicians like Rhazes (d. 925), Haly Abbas 982), Avicenna 1037), and Jorjani 1137) who discussed multiple aspects neuropathic including its classification, etiology, differentiating characteristics, qualities, pharmacologic nonpharmacologic treatments.2 Currently, neuropathy is a general term describing many signs symptoms caused by dysfunction nervous system.3 Peripheral neuropathies are largely associated with pins needles sensation, but also include range from paresthesias severe chronic dysesthesia. The burning polyneuropathy become so intense that it significantly impacts quality life. In order effectively treat neuropathy, essential determine underlying mechanism.3 According Levine (2018), diabetes mellitus, impaired glucose tolerance, primary systemic amyloidosis, familial Fabry disease, Lupus, vitamin B12 deficiency, celiac Sjögren’s syndrome, sarcoidosis, paraproteinemia, HIV, or paraneoplastic syndrome. addition, produced various immune-mediated responses, inherited diseases, alcohol abuse, chemotherapy, medications, trauma.4 Recently, SARS CoV-2 (COVID-19) has been reported produce possible up 2.3% patients hospitalized COVID-19, this prevalence probably underestimated because may develop months after injury system.5 Prevalence ranges 0.8 17.9%, an estimated male-to-female ratio 1:2; about 8% adults over 65 report some degree neuropathy.7,8